Old Malaria Drug as Good as Blockbuster Type 2 Diabetes Agent
“The old generic malaria drug hydroxychloroquine appears to have beneficial effects in patients with type 2 diabetes, new research suggests.”
Hydroxychloroquine Lowers HbA1c, BMI, and CRP
In the 24-week, multicenter, open-label study, the 87 patients with relatively recently diagnosed type 2 diabetes (average duration 6.1 years) and mean HbA1c of 8.4% who were taking metformin 2000 mg and vildagliptin 100 mg daily were randomized to add-on hydroxychloroquine 400 mg or canagliflozin 300 mg daily.
“Since 2014, hydroxychloroquine has been approved in India as an add-on for patients with type 2 diabetes who don’t achieve glycemic targets with two other oral glucose-lowering drugs, “which is quite a common scenario,” Gupta commented during his presentation.”
“Asked to comment, session moderator Lance Sloan, MD, medical director of the Texas Institute for Kidney and Endocrine Disorders, Lufkin, Texas, told Medscape Medical News: “I think it’s really fascinating that they’ve approved it for the treatment of diabetes in India. It’s really not on the radar here in this country.”
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