Repositioning of Hydroxychloroquine for Type 2 Diabetes
“A preclinical study conducted by Emami et al demonstrated that HCQ, by increasing intracellular pH, inhibits proteolytic enzymes responsible for degradation of insulin. Hence, the available insulin remains for a longer time.”
“Use of HCQ for 6 weeks in obese, non-diabetic subjects is associated with significant increase in insulin sensitivity index and trend towards reduced insulin resistance and insulin secretion”
“These results show a reduction in diabetes risk of up to 77% for patients taking HCQ for more than 4 years, a finding that is comparable or superior to that of other drugs studied in clinical trials”
“HCQ can emerge as an effective and well-tolerated treatment option for type 2 diabetes mellitus patients uncontrolled on sulfonylurea
and metformin combination”
“HCQ treated patients showed a significant fall in total cholesterol and
low-density lipoprotein from baseline. HCQ was found to be safe and well-tolerated”
http://www.jmgims.co.in/temp/JMahatmaGandhiInstMedSci2011-5130066_012530.pdf
Efficacy & safety of Hydroxychloroquine in the treatment of type 2 diabetes mellitus: a double blind, randomized comparison with pioglitazone
“Safe and well tolerated”
“Hydroxychloroquine may emerge as a well tolerated therapeutic option for T2DM patients uncontrolled on conventional therapy.”
Thank you President Trump / 2Q2Q Power back to the People .
This is a wonderful news
My dad has diabetes so im slowly bringing this up to him in little pieces. Everyone in my family already thinks im kinda out there. but everything thats happening with COVID and the HCQ i told them about in march so ive gained a little street cred with my dad lol!! cant scare him off with too much but he said we can sit down and talk next time.
Hi Paul,
The first link is unavailable, did you happen to save a hard copy?
Scott
here you go Scott. thanks for letting me know buddy
https://web.archive.org/web/20200402222313/https://ecancer.org/en/journal/article/781-repurposing-drugs-in-oncology-redo-chloroquine-and-hydroxychloroquine-as-anti-cancer-agents